Sunday, December 23, 2012

How Oncolytic Viruses Kill Cancer Cells: research, trials, cancer treatm...


How Oncolytic Viruses Kill Cancer Cells: research, clinical trials, cancer treatment, possible cure for cancer

More: http://www.virttu.com .  How oncolytic viruses work to kill cancer cells in melanoma, head and neck, prostate cancer and glioblastoma brain timours. Replication of oncolytic viruses inside tumours. Pre-clinical trials. Phase I, Phase II and Phase III clinical trials on oncolytics.  Use of oncolytic viruses to treat advanced malignant melanoma and mestatases – Amgen research using an oncolytic virus developed from HSV (Herpes Simplex Virus).  Problems with traditional chemotherapy – side effects.  Why Amgen bought an oncolytic viruse for $500m in cash and $500m to be paid if oncolytic trials are fully successful. Investor interest in oncolytic viruses.  Lessons from the history of research and development in monoclonal antibodies in cancer treatment. Why targeted cancer therapy – a so-called “magic bullet” is so needed.  How oncolytic viruses have been modified so that they cannot replicate in normal cells, but are still able to divide in a wide variety of human cancer cells. History of oncolytic viruses.  Arming oncolytic viruses. Using viruses like Seprehvir (HSV-1716), adapted to carry an additional payload: extra genes which teach infected cancer cells to take up a compound containing radioactive iodine from the blood, delivering a micro-dose of radiation inside individual cancer calls.  Or adding a gene which teaches cancer cells how to split a harmless pro-drug into two, inside the cell, releasing a very toxic chemo (alkylating agent).  Targetting oncolytic viruses – by adapting the feet of a virus to that they latch onto receptors on the surface of specific human cancer cells such as prostate.  Results of early Phase III Rheolysin clinical trials – combined oncolytic virus and cancer chemotherapy. Side effects and safety profile of oncolytic viruses in clinical studies.  FDA safety review of oncolytic viruses and approval for systemic administration of oncolytic viruses to children with advanced cancer. How genes work in viruses, and how genetic engineering allows us to cut and paste genes from one species into another. Patrick Dixon author of The Genetic Revolution, Chairman of Global Change Ltd, an advisor to many large pharma companies and to Virttu Biologics Ltd.

Saturday, November 05, 2011

Rejuvenation therapy - revitalize, renew, stop ageing, getting old - lat...



How scientists are discovering the secrets of eternal youth in animals -- and potentially in humans. How to stop getting old, turning off the normal physiology of ageing processes in human cells. Lessons from whales, rockfish project, turtles and parrots as well as other animals with longer lifespan. Impact on future life expectancy -- life insurance, pensions, unfunded pension liabilities, annuity rates, government debts, corporate pension fund valuations. Conference keynote speaker Patrick Dixon.

Thursday, July 21, 2011

Here Comes Radical Change: Future of Public Services, Demographics -- Ke...



Patrick Dixon -- conference keynote speaker -- impact of demographics, birth rates, youth, urban migration and immigration, life expectancy forecasts. All impact demand for public services, health care budgets, community services, demand for education, need for schools. Presentation for Welsh Parliament to public sector workers -- police officers, fire service, local councils, municipal authorities, teachers, social workers, health visitors, care assistants, community officers, health and safety advisors, government contractors and service providers. Changing culture, challenging structures and attitudes. Practical leadership lessons in change management for public sector workers. Team leadership and motivation to change working practices, encourage efficiency, cost savings, better standards, improved output and service impact.

Tuesday, June 28, 2011

Stop Getting Older - Anti-ageing research - stay young. Future Health -...



Antiageing therapies, science and research -- how to stop your biological clock. 65% of health care spending on people over 65 years old. Aging process -- physiology of aging and remedies, antiaging therapies. How to stay young. 7 key mechanisms of ageing in human cells. How we share common aging processes with many other animals. Shared genetic code and cell structures. Non-aging fish and whales. Genetic basis of ageing and aging as a treatable condition. Genetic damage inside nucleus of cell, damage to mitochondrial DNA. From health to performance, from sickness to wellness. Better memory, more energy, better sexual performance - Future of health care. Patrick Dixon is a health care keynote speaker at many health conferences. How patients, clients, over the counter therapy customers, and consumers of health care products will manage their own treatment. Patient choice and public health policy changes with government budget health cuts, health care rationing, post code lotteries. Private and public funding for health care treatment. How doctors and nurses will manage patients who often know more about their own medical condition, have made their own diagnosis, have made decisions about their own treatment (patient autonomy). Impact on over the counter pharmaceutical industry, chemists, drug stores, pharmacies and retail sales of health related products. Wellbeing, disease prevention, health promotion, vitamin and health supplements, dietary supplements. Future of the pharmaceutical industry with non-prescription medicines, remedies, therapies, drugs. Prescribing new treatments using new diagnostic tools, and patient clinical care pathways. Health policy development by governments, and health insurance companies. Patient survival and increase in life expectancy with early diagnosis and treatment using equipment bought by consumers for home use. Future of the NHS and national health service, medicare in America. Funding of health care in future -- people expected to fund their own health needs.

Stop getting old - science of ageing - how to stay young. Health keynot...



Mitochondria research -- improving memory, energy levels, use of food to create power inside cells. Antiageing therapies, science and research -- how to stop your biological clock. 65% of health care spending on people over 65 years old. Aging process -- physiology of aging and remedies, antiaging therapies. How to stay young. 7 key mechanisms of ageing in human cells. How we share common aging processes with many other animals. Shared genetic code and cell structures. Non-aging fish and whales. Genetic basis of ageing and aging as a treatable condition. Genetic damage inside nucleus of cell, damage to mitochondrial DNA. From health to performance, from sickness to wellness. Better memory, more energy, better sexual performance - Future of health care. Patrick Dixon is a health care keynote speaker at many health conferences. How patients, clients, over the counter therapy customers, and consumers of health care products will manage their own treatment. Patient choice and public health policy changes with government budget health cuts, health care rationing, post code lotteries. Private and public funding for health care treatment. How doctors and nurses will manage patients who often know more about their own medical condition, have made their own diagnosis, have made decisions about their own treatment (patient autonomy). Impact on over the counter pharmaceutical industry, chemists, drug stores, pharmacies and retail sales of health related products. Wellbeing, disease prevention, health promotion, vitamin and health supplements, dietary supplements. Future of the pharmaceutical industry with non-prescription medicines, remedies, therapies, drugs. Prescribing new treatments using new diagnostic tools, and patient clinical care pathways. Health policy development by governments, and health insurance companies. Patient survival and increase in life expectancy with early diagnosis and treatment using equipment bought by consumers for home use. Future of the NHS and national health service, medicare in America. Funding of health care in future -- people expected to fund their own health needs.

Alternative Therapies and Treatments - Physicians and Pharmaceutical Ind...



Alternative medicine, therapies, homeopathy, chiropractice, Antiageing therapies, science and research -- how to stop your biological clock. unmet medical needs. Traditional healers and herbal remedies. 65% of health care spending on people over 65 years old. Aging process -- physiology of aging and remedies, antiaging therapies. How to stay young. 7 key mechanisms of ageing in human cells. How we share common aging processes with many other animals. Shared genetic code and cell structures. Non-aging fish and whales. Genetic basis of ageing and aging as a treatable condition. Genetic damage inside nucleus of cell, damage to mitochondrial DNA. From health to performance, from sickness to wellness. Better memory, more energy, better sexual performance - Future of health care. Patrick Dixon is a health care keynote speaker at many health conferences. How patients, clients, over the counter therapy customers, and consumers of health care products will manage their own treatment. Patient choice and public health policy changes with government budget health cuts, health care rationing, post code lotteries. Private and public funding for health care treatment. How doctors and nurses will manage patients who often know more about their own medical condition, have made their own diagnosis, have made decisions about their own treatment (patient autonomy). Impact on over the counter pharmaceutical industry, chemists, drug stores, pharmacies and retail sales of health related products. Wellbeing, disease prevention, health promotion, vitamin and health supplements, dietary supplements. Future of the pharmaceutical industry with non-prescription medicines, remedies, therapies, drugs. Prescribing new treatments using new diagnostic tools, and patient clinical care pathways. Health policy development by governments, and health insurance companies. Patient survival and increase in life expectancy with early diagnosis and treatment using equipment bought by consumers for home use. Future of the NHS and national health service, medicare in America. Funding of health care in future -- people expected to fund their own health needs.

Get More Energy! Treatment for tiredeness, fatigue: Mitochondria researc...



Mitochondria research – improving memory, energy levels, use of food to create power inside cells. Treatments for chronic tiredeness and chronic fatigue syndrome. Antiageing therapies, science and research – how to stop your biological clock. 65% of health care spending on people over 65 years old. Aging process – physiology of aging and remedies, antiaging therapies. How to stay young. 7 key mechanisms of ageing in human cells. How we share common aging processes with many other animals. Shared genetic code and cell structures. Non-aging fish and whales. Genetic basis of ageing and aging as a treatable condition. Genetic damage inside nucleus of cell, damage to mitochondrial DNA. From health to performance, from sickness to wellness. Better memory, more energy, better sexual performance - Future of health care. Patrick Dixon is a health care keynote speaker at many health conferences. How patients, clients, over the counter therapy customers, and consumers of health care products will manage their own treatment. Patient choice and public health policy changes with government budget health cuts, health care rationing, post code lotteries. Private and public funding for health care treatment. How doctors and nurses will manage patients who often know more about their own medical condition, have made their own diagnosis, have made decisions about their own treatment (patient autonomy). Impact on over the counter pharmaceutical industry, chemists, drug stores, pharmacies and retail sales of health related products. Wellbeing, disease prevention, health promotion, vitamin and health supplements, dietary supplements. Future of the pharmaceutical industry with non-prescription medicines, remedies, therapies, drugs. Prescribing new treatments using new diagnostic tools, and patient clinical care pathways. Health policy development by governments, and health insurance companies. Patient survival and increase in life expectancy with early diagnosis and treatment using equipment bought by consumers for home use. Future of the NHS and national health service, medicare in America. Funding of health care in future – people expected to fund their own health needs.

Ageing nations - social and health impact of demographics - economy and ...



Ageing population, demographics, balance in age groups, birth rates and death rates. Population growth and decline. Baby boomers and baby boom. Migration and immigration patterns and public policies. Antiageing therapies, science and research -- how to stop your biological clock. 65% of health care spending on people over 65 years old. Aging process -- physiology of aging and remedies, antiaging therapies. How to stay young. 7 key mechanisms of ageing in human cells. How we share common aging processes with many other animals. Shared genetic code and cell structures. Non-aging fish and whales. Genetic basis of ageing and aging as a treatable condition. Genetic damage inside nucleus of cell, damage to mitochondrial DNA. From health to performance, from sickness to wellness. Better memory, more energy, better sexual performance - Future of health care. Patrick Dixon is a health care keynote speaker at many health conferences. How patients, clients, over the counter therapy customers, and consumers of health care products will manage their own treatment. Patient choice and public health policy changes with government budget health cuts, health care rationing, post code lotteries. Private and public funding for health care treatment. How doctors and nurses will manage patients who often know more about their own medical condition, have made their own diagnosis, have made decisions about their own treatment (patient autonomy). Impact on over the counter pharmaceutical industry, chemists, drug stores, pharmacies and retail sales of health related products. Wellbeing, disease prevention, health promotion, vitamin and health supplements, dietary supplements. Future of the pharmaceutical industry with non-prescription medicines, remedies, therapies, drugs. Prescribing new treatments using new diagnostic tools, and patient clinical care pathways. Health policy development by governments, and health insurance companies. Patient survival and increase in life expectancy with early diagnosis and treatment using equipment bought by consumers for home use. Future of the NHS and national health service, medicare in America. Funding of health care in future -- people expected to fund their own health needs.

Anti Ageing: Stop Your Biological Clock-- Future Health Care Speaker